The Pearson Lab integrates clinical expertise, mathematical modeling, high dimensional statistics, and basic tumor biology methods to investigate and propose new treatments for head and neck cancer.
University of Michigan
Ann Arbor, MI
Fellowship - Hematology/Oncology
2016
University of Michigan
Ann Arbor, MI
Postdoctoral Fellowship - Nor Lab (2013-2017)
2016
University of Michigan
Ann Arbor, MI
Residency - Internal Medicine
2012
University of Rochester
Rochester, NY
MD - Medicine
2010
University of Rochester
Rochester, NY
PhD - Statistics
2009
Cornell University
Ithaca, NY
BS - Biometry and Statistics
2002
Clinical trials of immunotherapy in triple-negative breast cancer.
Howard FM, Pearson AT, Nanda R. Clinical trials of immunotherapy in triple-negative breast cancer. Breast Cancer Res Treat. 2022 Aug; 195(1):1-15.
PMID: 35834065
Ovarian cancer through a multi-modal lens.
Hieromnimon HM, Pearson AT. Ovarian cancer through a multi-modal lens. Nat Cancer. 2022 06; 3(6):662-664.
PMID: 35764744
A global method for fast simulations of molecular dynamics in multiscale agent-based models of biological tissues.
Bergman D, Sweis RF, Pearson AT, Nazari F, Jackson TL. A global method for fast simulations of molecular dynamics in multiscale agent-based models of biological tissues. iScience. 2022 Jun 17; 25(6):104387.
PMID: 35637730
Development and Validation of a Decision Analytical Model for Posttreatment Surveillance for Patients With Oropharyngeal Carcinoma.
Nair V, Auger S, Kochanny S, Howard FM, Ginat D, Pasternak-Wise O, Juloori A, Koshy M, Izumchenko E, Agrawal N, Rosenberg A, Vokes EE, Skandari MR, Pearson AT. Development and Validation of a Decision Analytical Model for Posttreatment Surveillance for Patients With Oropharyngeal Carcinoma. JAMA Netw Open. 2022 04 01; 5(4):e227240.
PMID: 35416988
Classical mathematical models for prediction of response to chemotherapy and immunotherapy.
Ghaffari Laleh N, Loeffler CML, Grajek J, Stanková K, Pearson AT, Muti HS, Trautwein C, Enderling H, Poleszczuk J, Kather JN. Classical mathematical models for prediction of response to chemotherapy and immunotherapy. PLoS Comput Biol. 2022 02; 18(2):e1009822.
PMID: 35120124
Prospective study evaluating dynamic changes of cell-free HPV DNA in locoregional viral-associated oropharyngeal cancer treated with induction chemotherapy and response-adaptive treatment.
Rosenberg AJ, Izumchenko E, Pearson A, Gooi Z, Blair E, Karrison T, Juloori A, Ginat D, Cipriani N, Lingen M, Sloane H, Edelstein DL, Keyser K, Fredebohm J, Holtrup F, Jones FS, Haraf D, Agrawal N, Vokes EE. Prospective study evaluating dynamic changes of cell-free HPV DNA in locoregional viral-associated oropharyngeal cancer treated with induction chemotherapy and response-adaptive treatment. BMC Cancer. 2022 Jan 03; 22(1):17.
PMID: 34980038
Application of liquid biopsy as multi-functional biomarkers in head and neck cancer.
Mishra V, Singh A, Chen X, Rosenberg AJ, Pearson AT, Zhavoronkov A, Savage PA, Lingen MW, Agrawal N, Izumchenko E. Application of liquid biopsy as multi-functional biomarkers in head and neck cancer. Br J Cancer. 2022 02; 126(3):361-370.
PMID: 34876674
The IL-6R and Bmi-1 axis controls self-renewal and chemoresistance of head and neck cancer stem cells.
Herzog AE, Warner KA, Zhang Z, Bellile E, Bhagat MA, Castilho RM, Wolf GT, Polverini PJ, Pearson AT, Nör JE. The IL-6R and Bmi-1 axis controls self-renewal and chemoresistance of head and neck cancer stem cells. Cell Death Dis. 2021 10 23; 12(11):988.
PMID: 34689150
Risk and response adapted de-intensified treatment for HPV-associated oropharyngeal cancer: Optima paradigm expanded experience.
Rosenberg AJ, Agrawal N, Pearson A, Gooi Z, Blair E, Cursio J, Juloori A, Ginat D, Howard A, Chin J, Kochanny S, Foster C, Cipriani N, Lingen M, Izumchenko E, Seiwert TY, Haraf D, Vokes EE. Risk and response adapted de-intensified treatment for HPV-associated oropharyngeal cancer: Optima paradigm expanded experience. Oral Oncol. 2021 11; 122:105566.
PMID: 34662771
A robust and interpretable gene signature for predicting the lymph node status of primary T1/T2 oral cavity squamous cell carcinoma.
Ghantous Y, Omar M, Broner EC, Agrawal N, Pearson AT, Rosenberg AJ, Mishra V, Singh A, El-Naaj IA, Savage PA, Sidransky D, Marchionni L, Izumchenko E. A robust and interpretable gene signature for predicting the lymph node status of primary T1/T2 oral cavity squamous cell carcinoma. Int J Cancer. 2022 02 01; 150(3):450-460.
PMID: 34569064
Mark Roth Award
University of Michigan
2015
Chief Fellow in Hematology/Oncology
University of Michigan
2014 - 2015