David T. Rubin is the Joseph B. Kirsner Professor of Medicine, Professor of Pathology, Chief of the Section of Gastroenterology, Hepatology & Nutrition and Director of the Inflammatory Bowel Disease Center at the University of Chicago Medicine. He earned a medical degree with honors at The University of Chicago Pritzker School of Medicine where he also completed his residency in internal medicine and fellowships in gastroenterology and clinical medical ethics. He is associate faculty member at the MacLean Center for Clinical Medical Ethics, associate investigator at the University of Chicago Comprehensive Cancer Center and a member of the University of Chicago Committee on Clinical Pharmacology and Pharmacogenomics. He is the immediate past Chair of the National Scientific Advisory Committee of the Crohn’s & Colitis Foundation and current Chair of the International Organization for the Study of IBD.
Dr. Rubin’s research is focused on disease modification in IBD including clinical trial designs, novel measures of inflammation and prevention of adverse outcomes, and quality of life in IBD. He has twice received the ACG’s Governor’s Award of Excellence in Clinical Research (2003 and 2013), and in 2020, Dr. Rubin received the Sherman Prize for Excellence in Crohn’s and Colitis and in 2023, the UChicago Michael Reese Lectureship Award for outstanding faculty who have developed novel teaching and clinical research that advances healthcare, and separately, the distinguished UChicago Arthur H. Rubenstein Mentorship in Academic Medicine Award. He is Editor-in-Chief of the ACG On-Line Education Universe. Dr. Rubin is an editor of Curbside Consultation in IBD (3rd ed), senior editor of Sleisenger and Fordtran’s Gastrointestinal and Liver Disease (12th ed), and an author on >600 articles on management of IBD, including the 2019 and 2025 ACG Practice Guidelines for ulcerative colitis.
University of Chicago Pritzker School of Medicine
Chicago
Fellowship - Gastroenterology
2001
University of Chicago Pritzker School of Medicine
Chicago
Residency - Internal Medicine
1997
University of Chicago Pritzker School of Medicine
Chicago
MD
1994
University of Illinois
Urbana-Champaign
BS - Honors Biology
1990
International consensus on the use of intestinal ultrasound in inflammatory bowel disease trials.
International consensus on the use of intestinal ultrasound in inflammatory bowel disease trials. J Crohns Colitis. 2025 Sep 28; 19(9).
PMID: 40973472
International Magnetic Resonance Imaging Consensus for use in Luminal Crohn's Disease Trials and Clinical Practice.
International Magnetic Resonance Imaging Consensus for use in Luminal Crohn's Disease Trials and Clinical Practice. Clin Gastroenterol Hepatol. 2025 Aug 27.
PMID: 40882718
New Eczematous Eruption in Patients With Inflammatory Bowel Disease Who Stop Janus Kinase Inhibitors.
New Eczematous Eruption in Patients With Inflammatory Bowel Disease Who Stop Janus Kinase Inhibitors. Am J Gastroenterol. 2026 Jan 01; 121(1):268-273.
PMID: 40844618
School masking and COVID-19 community transmission: a synthetic control study.
School masking and COVID-19 community transmission: a synthetic control study. medRxiv. 2025 Aug 13.
PMID: 40832423
Real-world Experience of Upadacitinib Reinduction and High-dose Maintenance Therapy in Inflammatory Bowel Disease.
Real-world Experience of Upadacitinib Reinduction and High-dose Maintenance Therapy in Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2026 Mar; 24(3):763-771.
PMID: 40782945
Effect of gait retraining in minimalist footwear or barefoot on running footstrike and cadence: a systematic review.
Effect of gait retraining in minimalist footwear or barefoot on running footstrike and cadence: a systematic review. Res Sports Med. 2026 Mar-Apr; 34(2):163-175.
PMID: 40762620
A Guide to the Patient-Centric Use of Vedolizumab for Crohn's Disease.
A Guide to the Patient-Centric Use of Vedolizumab for Crohn's Disease. Inflamm Bowel Dis. 2025 Aug 01; 31(8):2269-2285.
PMID: 40512051
Incidence and Risk Factors for Development of Acne (JAKne) in Patients with Inflammatory Bowel Disease Treated With Upadacitinib.
Incidence and Risk Factors for Development of Acne (JAKne) in Patients with Inflammatory Bowel Disease Treated With Upadacitinib. Inflamm Bowel Dis. 2025 Aug 01; 31(8):2311-2314.
PMID: 40411447
Intestinal Ultrasound Identified Crohn's Disease In Previously Undiagnosed Siblings.
Intestinal Ultrasound Identified Crohn's Disease In Previously Undiagnosed Siblings. Inflamm Bowel Dis. 2025 Aug 01; 31(8):2315-2317.
PMID: 39903445
Comparative Effectiveness of Tofacitinib vs Upadacitinib for the Treatment of Acute Severe Ulcerative Colitis.
Comparative Effectiveness of Tofacitinib vs Upadacitinib for the Treatment of Acute Severe Ulcerative Colitis. Clin Gastroenterol Hepatol. 2026 Mar; 24(3):784-793.
PMID: 40721074