Dr. Missiakas’s research program examines the Gram-positive pathogens Staphylococcus aureus and Bacillus anthracis. This program seeks to appreciate the biogenesis of the envelope of these microorganisms as well as the secretion of their virulence factors and host pathways targeted by these pathogens.
Université of Paris XI
Orsay, France
Ph.D. - Biochemistry
1991
Inhibitory activities of monoclonal antibodies against Staphylococcus aureus clumping factor A.
Inhibitory activities of monoclonal antibodies against Staphylococcus aureus clumping factor A. mBio. 2025 Oct 08; 16(10):e0219725.
PMID: 40919922
A SpA+LukAB vaccine targeting Staphylococcus aureus evasion factors restricts infection in two minipig infection models.
A SpA+LukAB vaccine targeting Staphylococcus aureus evasion factors restricts infection in two minipig infection models. NPJ Vaccines. 2025 Apr 20; 10(1):78.
PMID: 40254611
A SecA-associated protease modulates the extent of surface display of staphylococcal protein A.
A SecA-associated protease modulates the extent of surface display of staphylococcal protein A. J Bacteriol. 2025 Apr 17; 207(4):e0052224.
PMID: 40135891
Reply to: Insufficient evidence for natural selection associated with the Black Death.
Reply to: Insufficient evidence for natural selection associated with the Black Death. Nature. 2025 Feb; 638(8051):E23-E29.
PMID: 39972229
A novel polysaccharide in the envelope of S. aureus influences the septal secretion of preproteins with a YSIRK/GXXS motif.
A novel polysaccharide in the envelope of S. aureus influences the septal secretion of preproteins with a YSIRK/GXXS motif. J Bacteriol. 2025 Feb 20; 207(2):e0047824.
PMID: 39873517
Screening a library of temperature-sensitive mutants to identify secretion factors in Staphylococcus aureus.
Screening a library of temperature-sensitive mutants to identify secretion factors in Staphylococcus aureus. J Bacteriol. 2025 Feb 20; 207(2):e0043324.
PMID: 39817767
Author Correction: Evolution of immune genes is associated with the Black Death.
Author Correction: Evolution of immune genes is associated with the Black Death. Nature. 2025 Jan; 637(8048):E30.
PMID: 39814901
Novel Antibody-Based Protection/Therapeutics in Staphylococcus aureus.
Novel Antibody-Based Protection/Therapeutics in Staphylococcus aureus. Annu Rev Microbiol. 2024 11; 78(1):425-446.
PMID: 39146354
PcdA promotes orthogonal division plane selection in Staphylococcus aureus.
PcdA promotes orthogonal division plane selection in Staphylococcus aureus. Nat Microbiol. 2024 Nov; 9(11):2997-3012.
PMID: 39468247
Deficiency in non-classical major histocompatibility class II-like molecule, H2-O confers protection against Staphylococcus aureus in mice.
Deficiency in non-classical major histocompatibility class II-like molecule, H2-O confers protection against Staphylococcus aureus in mice. PLoS Pathog. 2024 Jun; 20(6):e1012306.
PMID: 38843309