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Eduardo Perozo, PhD

Potassium dependent structural changes in the selectivity filter of HERG potassium channels.
Potassium dependent structural changes in the selectivity filter of HERG potassium channels. Nat Commun. 2024 Aug 29; 15(1):7470.
PMID: 39209832

Folding of prestin's anion-binding site and the mechanism of outer hair cell electromotility.
Folding of prestin's anion-binding site and the mechanism of outer hair cell electromotility. Elife. 2023 Dec 06; 12.
PMID: 38054956

Anionic omega currents from single countercharge mutants in the voltage-sensing domain of Ci-VSP.
Anionic omega currents from single countercharge mutants in the voltage-sensing domain of Ci-VSP. J Gen Physiol. 2024 01 01; 156(1).
PMID: 38019193

Folding of Prestin's Anion-Binding Site and the Mechanism of Outer Hair Cell Electromotility.
Folding of Prestin's Anion-Binding Site and the Mechanism of Outer Hair Cell Electromotility. bioRxiv. 2023 Oct 01.
PMID: 36909622

Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA.
Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA. J Mol Biol. 2023 09 01; 435(17):168192.
PMID: 37394032

Conformation-specific synthetic antibodies discriminate multiple functional states of the ion channel CorA.
Conformation-specific synthetic antibodies discriminate multiple functional states of the ion channel CorA. bioRxiv. 2023 May 07.
PMID: 37205530

State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels.
State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels. Elife. 2023 01 30; 12.
PMID: 36715097

Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP.
Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP. Proc Natl Acad Sci U S A. 2022 11; 119(44):e2206649119.
PMID: 36279472

Mechanism of voltage sensing in Ca2+- and voltage-activated K+ (BK) channels.
Mechanism of voltage sensing in Ca2+- and voltage-activated K+ (BK) channels. Proc Natl Acad Sci U S A. 2022 06 21; 119(25):e2204620119.
PMID: 35704760

Molecular determinants of inhibition of the human proton channel hHv1 by the designer peptide C6 and a bivalent derivative.
Molecular determinants of inhibition of the human proton channel hHv1 by the designer peptide C6 and a bivalent derivative. Proc Natl Acad Sci U S A. 2022 06 07; 119(23):e2120750119.
PMID: 35648818

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