Our Faculty

Eric A. Schwartz, MD

Molecular profiling of single circulating tumor cells from lung cancer patients.
Park SM, Wong DJ, Ooi CC, Kurtz DM, Vermesh O, Aalipour A, Suh S, Pian KL, Chabon JJ, Lee SH, Jamali M, Say C, Carter JN, Lee LP, Kuschner WG, Schwartz EJ, Shrager JB, Neal JW, Wakelee HA, Diehn M, Nair VS, Wang SX, Gambhir SS. Molecular profiling of single circulating tumor cells from lung cancer patients. Proc Natl Acad Sci U S A. 2016 12 27; 113(52):E8379-E8386.
PMID: 27956614

Dynorphin acts as a neuromodulator to inhibit itch in the dorsal horn of the spinal cord.
Kardon AP, Polgár E, Hachisuka J, Snyder LM, Cameron D, Savage S, Cai X, Karnup S, Fan CR, Hemenway GM, Bernard CS, Schwartz ES, Nagase H, Schwarzer C, Watanabe M, Furuta T, Kaneko T, Koerber HR, Todd AJ, Ross SE. Dynorphin acts as a neuromodulator to inhibit itch in the dorsal horn of the spinal cord. Neuron. 2014 May 07; 82(3):573-86.
PMID: 24726382

TRPV1 and TRPA1 antagonists prevent the transition of acute to chronic inflammation and pain in chronic pancreatitis.
Schwartz ES, La JH, Scheff NN, Davis BM, Albers KM, Gebhart GF. TRPV1 and TRPA1 antagonists prevent the transition of acute to chronic inflammation and pain in chronic pancreatitis. J Neurosci. 2013 Mar 27; 33(13):5603-11.
PMID: 23536075

Neurturin overexpression in skin enhances expression of TRPM8 in cutaneous sensory neurons and leads to behavioral sensitivity to cool and menthol.
Wang T, Jing X, DeBerry JJ, Schwartz ES, Molliver DC, Albers KM, Davis BM. Neurturin overexpression in skin enhances expression of TRPM8 in cutaneous sensory neurons and leads to behavioral sensitivity to cool and menthol. J Neurosci. 2013 Jan 30; 33(5):2060-70.
PMID: 23365243

NMDA receptors with incomplete Mg²? block enable low-frequency transmission through the cerebellar cortex.
Schwartz EJ, Rothman JS, Dugué GP, Diana M, Rousseau C, Silver RA, Dieudonné S. NMDA receptors with incomplete Mg²? block enable low-frequency transmission through the cerebellar cortex. J Neurosci. 2012 May 16; 32(20):6878-93.
PMID: 22593057

TRPV1 and TRPA1 function and modulation are target tissue dependent.
Malin S, Molliver D, Christianson JA, Schwartz ES, Cornuet P, Albers KM, Davis BM. TRPV1 and TRPA1 function and modulation are target tissue dependent. J Neurosci. 2011 Jul 20; 31(29):10516-28.
PMID: 21775597

Synergistic role of TRPV1 and TRPA1 in pancreatic pain and inflammation.
Schwartz ES, Christianson JA, Chen X, La JH, Davis BM, Albers KM, Gebhart GF. Synergistic role of TRPV1 and TRPA1 in pancreatic pain and inflammation. Gastroenterology. 2011 Apr; 140(4):1283-1291.e1-2.
PMID: 21185837

Persistent pain is dependent on spinal mitochondrial antioxidant levels.
Schwartz ES, Kim HY, Wang J, Lee I, Klann E, Chung JM, Chung K. Persistent pain is dependent on spinal mitochondrial antioxidant levels. J Neurosci. 2009 Jan 07; 29(1):159-68.
PMID: 19129394

Presynaptic G-protein-coupled receptors regulate synaptic cleft glutamate via transient vesicle fusion.
Schwartz EJ, Blackmer T, Gerachshenko T, Alford S. Presynaptic G-protein-coupled receptors regulate synaptic cleft glutamate via transient vesicle fusion. J Neurosci. 2007 May 30; 27(22):5857-68.
PMID: 17537956

5-HT prolongs ventral root bursting via presynaptic inhibition of synaptic activity during fictive locomotion in lamprey.
Schwartz EJ, Gerachshenko T, Alford S. 5-HT prolongs ventral root bursting via presynaptic inhibition of synaptic activity during fictive locomotion in lamprey. J Neurophysiol. 2005 Feb; 93(2):980-8.
PMID: 15456802

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