Our Faculty

Joseph A. Piccirilli, PhD

RNA-Puzzles Round V: blind predictions of 23 RNA structures.
RNA-Puzzles Round V: blind predictions of 23 RNA structures. Nat Methods. 2024 Dec 02.
PMID: 39623050

Post-transcriptional methylation of mitochondrial-tRNA differentially contributes to mitochondrial pathology.
Post-transcriptional methylation of mitochondrial-tRNA differentially contributes to mitochondrial pathology. Nat Commun. 2024 Oct 18; 15(1):9008.
PMID: 39424798

Mechanistic Studies of Small Molecule Ligands Selective to RNA Single G Bulges.
Mechanistic Studies of Small Molecule Ligands Selective to RNA Single G Bulges. bioRxiv. 2024 Oct 17.
PMID: 39464119

The Role of General Acid Catalysis in the Mechanism of an Alkyl Transferase Ribozyme.
The Role of General Acid Catalysis in the Mechanism of an Alkyl Transferase Ribozyme. ACS Catal. 2024 Oct 18; 14(20):15294-15305.
PMID: 39444533

A potential role for RNA aminoacylation prior to its role in peptide synthesis.
A potential role for RNA aminoacylation prior to its role in peptide synthesis. Proc Natl Acad Sci U S A. 2024 Aug 27; 121(35):e2410206121.
PMID: 39178230

Unraveling RNA Conformation Dynamics in Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episode Syndrome with Solid-State Nanopores.
Unraveling RNA Conformation Dynamics in Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episode Syndrome with Solid-State Nanopores. ACS Nano. 2024 Jul 02; 18(26):17240-17250.
PMID: 38906834

Structural basis for promiscuity in ligand recognition by yjdF riboswitch.
Structural basis for promiscuity in ligand recognition by yjdF riboswitch. Cell Discov. 2024 Apr 02; 10(1):37.
PMID: 38565535

Structure-guided aminoacylation and assembly of chimeric RNAs.
Structure-guided aminoacylation and assembly of chimeric RNAs. bioRxiv. 2024 Mar 03.
PMID: 38464152

Post-Transcriptional Methylation of Mitochondrial-tRNA Differentially Contributes to Mitochondrial Pathology.
Post-Transcriptional Methylation of Mitochondrial-tRNA Differentially Contributes to Mitochondrial Pathology. bioRxiv. 2023 Dec 10.
PMID: 38106193

Genome-Wide Profiling of tRNA Using an Unexplored Reverse Transcriptase with High Processivity.
Genome-Wide Profiling of tRNA Using an Unexplored Reverse Transcriptase with High Processivity. bioRxiv. 2023 Dec 09.
PMID: 38106225

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