Margo Emont, PhD, studies adipocyte development and function. She trained at the University of Michigan and Beth Israel Deaconess Medical Center, working on projects characterizing both white and thermogenic adipocytes. Her lab now uses technologies such as single nuclear RNA sequencing to profile the cell types in adipose tissue and to understand how adipose tissue and adipocytes change under different physiological states. Her lab is also focused on understanding how to drive adipocytes towards or away from certain states with a goal of improving metabolic health through modification of adipocyte function.
Transcriptional and epigenomic analysis of insulin sensitivity in human adipocytes.
Transcriptional and epigenomic analysis of insulin sensitivity in human adipocytes. Cell Rep. 2026 Sep 25; 45(10):118042.
PMID: 42789384
Understanding adipocyte heterogeneity across species, depot, and disease.
Understanding adipocyte heterogeneity across species, depot, and disease. Biochem Soc Trans. 2026 Aug 26; 54(8):959-972.
PMID: 42495785
Natural microbiota confer life-long protection against obesity via an early-life, immune-mediated effect on brown adipocytes.
Natural microbiota confer life-long protection against obesity via an early-life, immune-mediated effect on brown adipocytes. Gut Microbes. 2026 Dec 31; 18(1):2718613.
PMID: 42634246
Rapid Remodeling of Human White Adipose Tissue Following Bariatric Surgery.
Rapid Remodeling of Human White Adipose Tissue Following Bariatric Surgery. bioRxiv. 2026 Apr 15.
PMID: 42039637
Defining the vascular niche of human adipose tissue across metabolic states.
Defining the vascular niche of human adipose tissue across metabolic states. Nat Metab. 2026 Mar; 8(3):722-740.
PMID: 41820564
Cytoarchitectural multi-depot profiling reveals immune-metabolic crosstalk in human colon-associated adipose tissue.
Cytoarchitectural multi-depot profiling reveals immune-metabolic crosstalk in human colon-associated adipose tissue. Cell Metab. 2026 Feb 03; 38(2):419-433.e9.
PMID: 41534526
Influence of Weight Loss and Weight Regain on Adipose Tissue Inflammation.
Influence of Weight Loss and Weight Regain on Adipose Tissue Inflammation. Arterioscler Thromb Vasc Biol. 2025 12; 45(12):2155-2163.
PMID: 41036560
Defining the vascular niche of human adipose tissue across metabolic states.
Defining the vascular niche of human adipose tissue across metabolic states. bioRxiv. 2025 Sep 22.
PMID: 41040169
Weight loss alters adipose tissue beyond just reducing fat.
Weight loss alters adipose tissue beyond just reducing fat. Nature. 2025 Aug; 644(8077):616-617.
PMID: 40634572
The extracellular vesicle transcriptome provides tissue-specific functional genomic annotation relevant to disease susceptibility in obesity.
The extracellular vesicle transcriptome provides tissue-specific functional genomic annotation relevant to disease susceptibility in obesity. Cell Genom. 2025 09 10; 5(9):100925.
PMID: 40669467