My lab studies how populations of neurons implement decision making and motor control. We record and manipulate the activity of hundreds or thousands of neurons in mouse cortex, then use sophisticated analyses to understand how these areas compute variables that the animal needs in order to behave. With calcium imaging, we can identify each neuron's cell type, layer, or projection pattern, and use this information to better understand inter-area communication and the organization of computation within cortex. With optogenetics, we can close the causal loop to determine if the activity is necessary or the roles of cell types in computation. Finally, with pharmacological manipulations, we can begin to understand how psychiatric drugs drive their behavioral effects.
Cold Spring Harbor Laboratory
Cold Spring Harbor, NY
- Neuroscience
2018
Stanford University
Stanford, CA
PhD - Neuroscience
2011
Stanford University
Stanford, CA
BS - Symbolic Systems
2005
Combatting nonidentifiability to infer motor cortex inputs yields similar encoding of initial and corrective movements.
Combatting nonidentifiability to infer motor cortex inputs yields similar encoding of initial and corrective movements. bioRxiv. 2025 Sep 11.
PMID: 40964298
Increasing Access to Physical Activity Opportunities for Patients: A Review.
Increasing Access to Physical Activity Opportunities for Patients: A Review. Am J Lifestyle Med. 2025 Jun 05; 15598276251348174.
PMID: 40485746
Reach-dependent reorientation of rotational dynamics in motor cortex.
Reach-dependent reorientation of rotational dynamics in motor cortex. Nat Commun. 2024 Aug 15; 15(1):7007.
PMID: 39143078
Analysis of Common Exercise Modalities in Improving Athletic Performance in Older Adults: A Narrative Review.
Analysis of Common Exercise Modalities in Improving Athletic Performance in Older Adults: A Narrative Review. Curr Sports Med Rep. 2024 Jun 01; 23(6):245-252.
PMID: 38838688
Microstimulation of human somatosensory cortex evokes task-dependent, spatially patterned responses in motor cortex.
Microstimulation of human somatosensory cortex evokes task-dependent, spatially patterned responses in motor cortex. Nat Commun. 2023 11 10; 14(1):7270.
PMID: 37949923
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution.
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution. Nat Neurosci. 2022 12; 25(12):1724-1734.
PMID: 36424431
The implications of categorical and category-free mixed selectivity on representational geometries.
The implications of categorical and category-free mixed selectivity on representational geometries. Curr Opin Neurobiol. 2022 12; 77:102644.
PMID: 36332415
Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia.
Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia. Front Oncol. 2022; 12:897280.
PMID: 35903706
Glucocorticoid-induced osteonecrosis in systemic lupus erythematosus patients.
Glucocorticoid-induced osteonecrosis in systemic lupus erythematosus patients. Clin Transl Med. 2021 10; 11(10):e526.
PMID: 34709753
BRICseq Bridges Brain-wide Interregional Connectivity to Neural Activity and Gene Expression in Single Animals.
BRICseq Bridges Brain-wide Interregional Connectivity to Neural Activity and Gene Expression in Single Animals. Cell. 2020 Dec 23; 183(7):2040.
PMID: 33357401
McKnight Foundation Allison Doupe Fellowship
Cold Spring Harbor Laboratory
2015 - 2015
Simons Collaboration on the Global Brain postdoctoral fellowship
Cold Spring Harbor Laboratory
2015 - 2018
Swartz Postdoctoral Fellowship
Cold Spring Harbor Laboratory
2013 - 2015
NSF GRFP
Stanford University
2006 - 2010