In my research, I develop computational and statistical methods for population genomics analysis to investigate the forces underlying evolution and genetic variation in populations. Specifically, some things we work on are inferring demographic histories, and studying adaptation using ancient DNA or time series genetic data.
Technical University Berlin
Berlin
PhD - Mathematics
2009
Bielefeld University
Bielefeld
Diplom - Computer Science
2006
The TMRCA of general genealogies in populations with deterministically varying size.
The TMRCA of general genealogies in populations with deterministically varying size. Theor Popul Biol. 2025 Oct; 165:1-9.
PMID: 40614870
Population Genomic Scans for Natural Selection and Demography.
Population Genomic Scans for Natural Selection and Demography. Annu Rev Genet. 2024 11; 58(1):319-339.
PMID: 39227130
Inference of population history using coalescent HMMs: review and outlook.
Inference of population history using coalescent HMMs: review and outlook. Curr Opin Genet Dev. 2018 12; 53:70-76.
PMID: 30056275
Model-based detection and analysis of introgressed Neanderthal ancestry in modern humans.
Model-based detection and analysis of introgressed Neanderthal ancestry in modern humans. Mol Ecol. 2018 10; 27(19):3873-3888.
PMID: 29603507
Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans.
Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans. Nature. 2018 01 11; 553(7687):203-207.
PMID: 29323294
Computing the joint distribution of the total tree length across loci in populations with variable size.
Computing the joint distribution of the total tree length across loci in populations with variable size. Theor Popul Biol. 2017 12; 118:1-19.
PMID: 28943126
The Effects of Population Size Histories on Estimates of Selection Coefficients from Time-Series Genetic Data.
The Effects of Population Size Histories on Estimates of Selection Coefficients from Time-Series Genetic Data. Mol Biol Evol. 2016 11; 33(11):3002-3027.
PMID: 27550904
SpectralTDF: transition densities of diffusion processes with time-varying selection parameters, mutation rates and effective population sizes.
SpectralTDF: transition densities of diffusion processes with time-varying selection parameters, mutation rates and effective population sizes. Bioinformatics. 2016 03 01; 32(5):795-7.
PMID: 26556388
POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans.
POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans. Science. 2015 Aug 21; 349(6250):aab3884.
PMID: 26198033
Transition Densities and Sample Frequency Spectra of Diffusion Processes with Selection and Variable Population Size.
Transition Densities and Sample Frequency Spectra of Diffusion Processes with Selection and Variable Population Size. Genetics. 2015 Jun; 200(2):601-17.
PMID: 25873633
Postdoctoral Research Fellowship
German Research Foundation (DFG)
2011 - 2013
Ph.D. Fellowship, International Research Training Group
TU Berlin
2006 - 2009