Dr. Nathan Schoettler specializes in the care of patients with acute and chronic respiratory diseases, including asthma, as well as critically ill patients. His clinical practice focuses on delivering comprehensive, evidence-based care.
Dr. Schoettler’s research centers on the immunologic and genetic mechanisms that drive asthma and related respiratory diseases. His work integrates human cohort studies with mechanistic approaches to uncover how airway inflammation varies across disease phenotypes. He aims to identify molecular pathways that could inform precision medicine strategies and improve therapeutic responses. Ultimately, his research seeks to translate biological insights into targeted interventions for patients with difficult-to-treat asthma.
University of Chicago
Chicago, IL
Postdoctoral research - Human Genetics
2019
University of Chicago
Chicago, IL
MD - Medicine
2012
University of Chicago
Chicago, IL
PhD - Immunology
2009
University of California, Los Angeles
Los Angeles, CA
MS - Molecular, Cellular and Developmental Biology
2003
Shared loci but distinct variants underlie genetic architecture of allergic diseases.
Shared loci but distinct variants underlie genetic architecture of allergic diseases. medRxiv. 2025 Jun 07.
PMID: 40502601
Integration of functional genomics and statistical fine-mapping systematically characterizes adult-onset and childhood-onset asthma genetic associations.
Integration of functional genomics and statistical fine-mapping systematically characterizes adult-onset and childhood-onset asthma genetic associations. Genome Med. 2025 Apr 10; 17(1):35.
PMID: 40205616
Early-life wheeze trajectories are associated with distinct asthma transcriptomes later in life.
Early-life wheeze trajectories are associated with distinct asthma transcriptomes later in life. J Allergy Clin Immunol. 2025 Sep; 156(3):640-650.
PMID: 40189159
Comparison of Race-Neutral versus Race-Specific Spirometry Equations for Evaluation of Child Asthma.
Comparison of Race-Neutral versus Race-Specific Spirometry Equations for Evaluation of Child Asthma. Am J Respir Crit Care Med. 2025 Mar; 211(3):464-476.
PMID: 39642347
Integration of functional genomics and statistical fine-mapping systematically characterizes adult-onset and childhood-onset asthma genetic associations.
Integration of functional genomics and statistical fine-mapping systematically characterizes adult-onset and childhood-onset asthma genetic associations. medRxiv. 2025 Feb 17.
PMID: 40034789
Comparison of Race-neutral Versus Race-specific Spirometry Equations for Evaluation of Child Asthma.
Comparison of Race-neutral Versus Race-specific Spirometry Equations for Evaluation of Child Asthma. Am J Respir Crit Care Med. 2024 Dec 06.
PMID: 39642347
Advances in asthma and allergic disease genetics.
Advances in asthma and allergic disease genetics. Curr Opin Allergy Clin Immunol. 2025 Feb 01; 25(1):58-65.
PMID: 39641751
Dynamic responses of human lung innate and adaptive immune cells highlight the roles of genes at asthma risk loci.
Dynamic responses of human lung innate and adaptive immune cells highlight the roles of genes at asthma risk loci. bioRxiv. 2024 Sep 24.
PMID: 39386483
Screening asthmatics for atopic status using the ALergy EXplorer (ALEX2) macroarray.
Screening asthmatics for atopic status using the ALergy EXplorer (ALEX2) macroarray. J Asthma. 2024 Sep; 61(9):1050-1057.
PMID: 38415683
Revealing polygenic pleiotropy using genetic risk scores for asthma.
Revealing polygenic pleiotropy using genetic risk scores for asthma. HGG Adv. 2023 10 12; 4(4):100233.
PMID: 37663543