We study human genomic factors that control and interact with the microbiome. We utilize high-throughput genomics technologies and employ computational, statistical, machine learning, and population genetic analytical approaches, with the goal of understanding how we interact with our microbial communities, how host-microbe interactions affect human disease, and how the symbiosis between us and our microbiome evolved.
Maternal Physical Activity and its Relationship to the Human Milk Metabolome and Infant Body Composition.
Maternal Physical Activity and its Relationship to the Human Milk Metabolome and Infant Body Composition. J Clin Endocrinol Metab. 2025 May 26.
PMID: 40417941
Microbes with higher metabolic independence are enriched in human gut microbiomes under stress.
Microbes with higher metabolic independence are enriched in human gut microbiomes under stress. Elife. 2025 May 16; 12.
PMID: 40377187
Social and environmental predictors of gut microbiome age in wild baboons.
Social and environmental predictors of gut microbiome age in wild baboons. Elife. 2025 Apr 17; 13.
PMID: 40244653
How scientists and institutions should respond.
How scientists and institutions should respond. Elife. 2025 Mar 25; 14.
PMID: 40130608
Cardiometabolic disease risk in gorillas is associated with altered gut microbial metabolism.
Cardiometabolic disease risk in gorillas is associated with altered gut microbial metabolism. NPJ Biofilms Microbiomes. 2025 Feb 21; 11(1):33.
PMID: 39984469
Integration of 168,000 samples reveals global patterns of the human gut microbiome.
Integration of 168,000 samples reveals global patterns of the human gut microbiome. Cell. 2025 Feb 20; 188(4):1100-1118.e17.
PMID: 39848248
Social and environmental predictors of gut microbiome age in wild baboons.
Social and environmental predictors of gut microbiome age in wild baboons. bioRxiv. 2024 Dec 24.
PMID: 39131274
Human milk variation is shaped by maternal genetics and impacts the infant gut microbiome.
Human milk variation is shaped by maternal genetics and impacts the infant gut microbiome. Cell Genom. 2024 Oct 09; 4(10):100638.
PMID: 39265573
Microbes with higher metabolic independence are enriched in human gut microbiomes under stress.
Microbes with higher metabolic independence are enriched in human gut microbiomes under stress. bioRxiv. 2024 Jul 26.
PMID: 37293035
Human cytomegalovirus in breast milk is associated with milk composition and the infant gut microbiome and growth.
Human cytomegalovirus in breast milk is associated with milk composition and the infant gut microbiome and growth. Nat Commun. 2024 Jul 23; 15(1):6216.
PMID: 39043677