We study human genomic factors that control and interact with the microbiome. We utilize high-throughput genomics technologies and employ computational, statistical, machine learning, and population genetic analytical approaches, with the goal of understanding how we interact with our microbial communities, how host-microbe interactions affect human disease, and how the symbiosis between us and our microbiome evolved.
Human milk variation is shaped by maternal genetics and impacts the infant gut microbiome.
Human milk variation is shaped by maternal genetics and impacts the infant gut microbiome. Cell Genom. 2024 Oct 09; 4(10):100638.
PMID: 39265573
Social and environmental predictors of gut microbiome age in wild baboons.
Social and environmental predictors of gut microbiome age in wild baboons. bioRxiv. 2024 Aug 04.
PMID: 39131274
Microbes with higher metabolic independence are enriched in human gut microbiomes under stress.
Microbes with higher metabolic independence are enriched in human gut microbiomes under stress. bioRxiv. 2024 Jul 26.
PMID: 37293035
Human cytomegalovirus in breast milk is associated with milk composition and the infant gut microbiome and growth.
Human cytomegalovirus in breast milk is associated with milk composition and the infant gut microbiome and growth. Nat Commun. 2024 Jul 23; 15(1):6216.
PMID: 39043677
Temporal patterns of gut microbiota in lemurs (Eulemur rubriventer) living in intact and disturbed habitats in a novel sample type.
Temporal patterns of gut microbiota in lemurs (Eulemur rubriventer) living in intact and disturbed habitats in a novel sample type. Am J Primatol. 2024 Jun 14; e23656.
PMID: 38873762
Assembly, stability, and dynamics of the infant gut microbiome are linked to bacterial strains and functions in mother's milk.
Assembly, stability, and dynamics of the infant gut microbiome are linked to bacterial strains and functions in mother's milk. bioRxiv. 2024 Jan 28.
PMID: 38328166
Multi-omic approaches for host-microbiome data integration.
Multi-omic approaches for host-microbiome data integration. Gut Microbes. 2024 Jan-Dec; 16(1):2297860.
PMID: 38166610
Integration of 168,000 samples reveals global patterns of the human gut microbiome.
Integration of 168,000 samples reveals global patterns of the human gut microbiome. bioRxiv. 2023 Oct 11.
PMID: 37873416
Human Cytomegalovirus in breast milk is associated with milk composition, the infant gut microbiome, and infant growth.
Human Cytomegalovirus in breast milk is associated with milk composition, the infant gut microbiome, and infant growth. bioRxiv. 2023 Jul 19.
PMID: 37503212
Microbes with higher metabolic independence are enriched in human gut microbiomes under stress.
Microbes with higher metabolic independence are enriched in human gut microbiomes under stress. bioRxiv. 2023 May 26.
PMID: 37293035