Dr. Groman is an Assistant Professor in the Department of Anesthesia and Critical Care at the University of Chicago. Her research program is investigating the neurobiological mechanisms of decision-making in normal and pathological states, with a particular interest in addiction. Her lab integrates behavioral paradigms with computational analyses, neuroimaging approaches, systems-level manipulations, and molecular analyses in rodents to generate mechanistic links between genes, signaling mechanisms, and behavior that can help us understand the pathology of addiction.
Reward-Mediated, Model-Free Reinforcement-Learning Mechanisms in Pavlovian and Instrumental Tasks Are Related.
Reward-Mediated, Model-Free Reinforcement-Learning Mechanisms in Pavlovian and Instrumental Tasks Are Related. J Neurosci. 2023 01 18; 43(3):458-471.
PMID: 36216504
Examining sex differences in responses to footshock stress and the role of the metabotropic glutamate receptor 5: an [18F]FPEB and positron emission tomography study in rats.
Examining sex differences in responses to footshock stress and the role of the metabotropic glutamate receptor 5: an [18F]FPEB and positron emission tomography study in rats. Neuropsychopharmacology. 2023 02; 48(3):489-497.
PMID: 36100654
Adolescent reinforcement-learning trajectories predict cocaine-taking behaviors in adult male and female rats.
Adolescent reinforcement-learning trajectories predict cocaine-taking behaviors in adult male and female rats. Psychopharmacology (Berl). 2022 Sep; 239(9):2885-2901.
PMID: 35705734
Imaging the fetal nonhuman primate brain with SV2A positron emission tomography (PET).
Imaging the fetal nonhuman primate brain with SV2A positron emission tomography (PET). Eur J Nucl Med Mol Imaging. 2022 09; 49(11):3679-3691.
PMID: 35633376
MicroPET evidence for a hypersensitive neuroinflammatory profile of gp120 mouse model of HIV.
MicroPET evidence for a hypersensitive neuroinflammatory profile of gp120 mouse model of HIV. Psychiatry Res Neuroimaging. 2022 04; 321:111445.
PMID: 35101828
Reinforcement learning detuned in addiction: integrative and translational approaches.
Reinforcement learning detuned in addiction: integrative and translational approaches. Trends Neurosci. 2022 02; 45(2):96-105.
PMID: 34920884
Paranoia and belief updating during the COVID-19 crisis.
Paranoia and belief updating during the COVID-19 crisis. Nat Hum Behav. 2021 09; 5(9):1190-1202.
PMID: 34316049
Unlocking the reinforcement-learning circuits of the orbitofrontal cortex.
Unlocking the reinforcement-learning circuits of the orbitofrontal cortex. Behav Neurosci. 2021 Apr; 135(2):120-128.
PMID: 34060870
The effects of fatty acid amide hydrolase inhibition and monoacylglycerol lipase inhibition on habit formation in mice.
The effects of fatty acid amide hydrolase inhibition and monoacylglycerol lipase inhibition on habit formation in mice. Eur J Neurosci. 2022 02; 55(4):922-938.
PMID: 33506530
Paranoia and belief updating during a crisis.
Paranoia and belief updating during a crisis. Res Sq. 2021 Jan 18.
PMID: 33469574