Stephen C. Meredith, MD PhD

Serine 408 phosphorylation is a molecular switch that regulates structure and function of the occludin a-helical bundle.
Serine 408 phosphorylation is a molecular switch that regulates structure and function of the occludin a-helical bundle. Proc Natl Acad Sci U S A. 2022 08 23; 119(34):e2204618119.
PMID: 35969745

Sensitivity-Enhanced Solid-State NMR Detection of Structural Differences and Unique Polymorphs in Pico- to Nanomolar Amounts of Brain-Derived and Synthetic 42-Residue Amyloid-ß Fibrils.
Sensitivity-Enhanced Solid-State NMR Detection of Structural Differences and Unique Polymorphs in Pico- to Nanomolar Amounts of Brain-Derived and Synthetic 42-Residue Amyloid-ß Fibrils. J Am Chem Soc. 2021 08 04; 143(30):11462-11472.
PMID: 34308630

Molecular dynamics study of water channels in natural and synthetic amyloid-ß fibrils.
Molecular dynamics study of water channels in natural and synthetic amyloid-ß fibrils. J Chem Phys. 2021 Jun 21; 154(23):235102.
PMID: 34241272

Nanodroplet Oligomers (NanDOs) of Aß40.
Nanodroplet Oligomers (NanDOs) of Aß40. Biochemistry. 2021 09 14; 60(36):2691-2703.
PMID: 34029056

Atomic-level differences between brain parenchymal- and cerebrovascular-seeded Aß fibrils.
Atomic-level differences between brain parenchymal- and cerebrovascular-seeded Aß fibrils. Sci Rep. 2021 01 08; 11(1):247.
PMID: 33420184

Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer.
Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer. Epigenetics. 2021 12; 16(12):1317-1334.
PMID: 33356812

Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell.
Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell. JCI Insight. 2019 Dec 05; 4(23).
PMID: 31801912

ß-amyloid model core peptides: Effects of hydrophobes and disulfides.
ß-amyloid model core peptides: Effects of hydrophobes and disulfides. Protein Sci. 2020 02; 29(2):527-541.
PMID: 31710741

Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell.
Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell. JCI Insight. 2019 11 01; 4(21).
PMID: 31672936

ß-Amyloid aggregation and heterogeneous nucleation.
ß-Amyloid aggregation and heterogeneous nucleation. Protein Sci. 2019 09; 28(9):1567-1581.
PMID: 31276610