Dr. Liu's research focuses on uncovering the genetic basis and biological mechanisms of disease through the integration of computational genomics, statistical genetics, and human genetics. Dr. Liu is particularly interested in interpreting disease-associated genetic variants using functional genomics, single-cell omics, and gene regulatory networks. The lab also has a broad interest in understanding the genetic architectures of diseases across diverse populations and in enhancing the portability and accuracy of genetic prediction models.
Harvard School of Public Health
Boston, USA
Postdoc - Statistical Genetics
2017
National University of Singapore
Singapore, Singapore
PHD - Population Genetics
2014
National University of Singapore
Singapore, Singapore
Bachelor of Science - Computational Biology
2010
Allele frequency impacts the cross-ancestry portability of gene expression prediction in lymphoblastoid cell lines.
Allele frequency impacts the cross-ancestry portability of gene expression prediction in lymphoblastoid cell lines. Am J Hum Genet. 2024 Dec 05; 111(12):2814-2825.
PMID: 39549695
GBAT: a gene-based association test for robust detection of trans-gene regulation.
GBAT: a gene-based association test for robust detection of trans-gene regulation. Genome Biol. 2020 08 24; 21(1):211.
PMID: 32831138
Trans Effects on Gene Expression Can Drive Omnigenic Inheritance.
Trans Effects on Gene Expression Can Drive Omnigenic Inheritance. Cell. 2019 05 02; 177(4):1022-1034.e6.
PMID: 31051098