Our Faculty

Shabaana Khader, PhD

Nuclear Factor ?B Signaling Deficiency in CD11c-Expressing Phagocytes Mediates Early Inflammatory Responses and Enhances Mycobacterium tuberculosis Control.
Nuclear Factor ?B Signaling Deficiency in CD11c-Expressing Phagocytes Mediates Early Inflammatory Responses and Enhances Mycobacterium tuberculosis Control. J Infect Dis. 2024 Aug 16; 230(2):336-345.
PMID: 38324907

BCG vaccination alters the epigenetic landscape of progenitor cells in human bone marrow to influence innate immune responses.
BCG vaccination alters the epigenetic landscape of progenitor cells in human bone marrow to influence innate immune responses. Immunity. 2024 Sep 10; 57(9):2095-2107.e8.
PMID: 39153479

Development of Luminescent Biosensors for Calprotectin.
Development of Luminescent Biosensors for Calprotectin. ACS Chem Biol. 2024 Jun 21; 19(6):1250-1259.
PMID: 38843544

Vaccination with Mincle agonist UM-1098 and mycobacterial antigens induces protective Th1 and Th17 responses.
Vaccination with Mincle agonist UM-1098 and mycobacterial antigens induces protective Th1 and Th17 responses. NPJ Vaccines. 2024 Jun 06; 9(1):100.
PMID: 38844494

A protective role for type I interferon signaling following infection with Mycobacterium tuberculosis carrying the rifampicin drug resistance-conferring RpoB mutation H445Y.
A protective role for type I interferon signaling following infection with Mycobacterium tuberculosis carrying the rifampicin drug resistance-conferring RpoB mutation H445Y. PLoS Pathog. 2024 Apr; 20(4):e1012137.
PMID: 38603763

Phospholipase C epsilon-1 (PLC?1) mediates macrophage activation and protection against tuberculosis.
Phospholipase C epsilon-1 (PLC?1) mediates macrophage activation and protection against tuberculosis. Infect Immun. 2024 Apr 09; 92(4):e0049523.
PMID: 38451080

Lung type 3 innate lymphoid cells respond early following Mycobacterium tuberculosis infection.
Lung type 3 innate lymphoid cells respond early following Mycobacterium tuberculosis infection. mBio. 2024 Apr 10; 15(4):e0329923.
PMID: 38407132

Saponin TQL1055 adjuvant-containing vaccine confers protection upon Mycobacterium tuberculosis challenge in mice.
Saponin TQL1055 adjuvant-containing vaccine confers protection upon Mycobacterium tuberculosis challenge in mice. Hum Vaccin Immunother. 2024 Dec 31; 20(1):2302070.
PMID: 38190806

Elevated Level of Circulating but Not Urine S100A8/A9 Identifies Poor COVID-19 Outcomes.
Elevated Level of Circulating but Not Urine S100A8/A9 Identifies Poor COVID-19 Outcomes. ACS Infect Dis. 2023 10 13; 9(10):1815-1820.
PMID: 37787461

Mycobacterium tuberculosis infection drives differential responses in the bone marrow hematopoietic stem and progenitor cells.
Mycobacterium tuberculosis infection drives differential responses in the bone marrow hematopoietic stem and progenitor cells. Infect Immun. 2023 10 17; 91(10):e0020123.
PMID: 37754680

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