Our Faculty

Shabaana Khader, PhD

A protective role for type I interferon signaling following infection with Mycobacterium tuberculosis carrying the rifampicin drug resistance-conferring RpoB mutation H445Y.
A protective role for type I interferon signaling following infection with Mycobacterium tuberculosis carrying the rifampicin drug resistance-conferring RpoB mutation H445Y. PLoS Pathog. 2024 Apr 11; 20(4):e1012137.
PMID: 38603763

Phospholipase C epsilon-1 (PLC?1) mediates macrophage activation and protection against tuberculosis.
Phospholipase C epsilon-1 (PLC?1) mediates macrophage activation and protection against tuberculosis. Infect Immun. 2024 Apr 09; 92(4):e0049523.
PMID: 38451080

Lung type 3 innate lymphoid cells respond early following Mycobacterium tuberculosis infection.
Lung type 3 innate lymphoid cells respond early following Mycobacterium tuberculosis infection. mBio. 2024 Apr 10; 15(4):e0329923.
PMID: 38407132

NF-?B signaling deficiency in CD11c-expressing phagocytes mediates early inflammatory responses and enhances Mycobacterium tuberculosis control.
NF-?B signaling deficiency in CD11c-expressing phagocytes mediates early inflammatory responses and enhances Mycobacterium tuberculosis control. J Infect Dis. 2024 Feb 07.
PMID: 38324907

Saponin TQL1055 adjuvant-containing vaccine confers protection upon Mycobacterium tuberculosis challenge in mice.
Saponin TQL1055 adjuvant-containing vaccine confers protection upon Mycobacterium tuberculosis challenge in mice. Hum Vaccin Immunother. 2024 Dec 31; 20(1):2302070.
PMID: 38190806

Elevated Level of Circulating but Not Urine S100A8/A9 Identifies Poor COVID-19 Outcomes.
Elevated Level of Circulating but Not Urine S100A8/A9 Identifies Poor COVID-19 Outcomes. ACS Infect Dis. 2023 10 13; 9(10):1815-1820.
PMID: 37787461

Mycobacterium tuberculosis infection drives differential responses in the bone marrow hematopoietic stem and progenitor cells.
Mycobacterium tuberculosis infection drives differential responses in the bone marrow hematopoietic stem and progenitor cells. Infect Immun. 2023 10 17; 91(10):e0020123.
PMID: 37754680

Mycobacterium tuberculosis carrying the rifampicin drug-resistance-conferring rpoB mutation H445Y is associated with suppressed immunity through type I interferons.
Mycobacterium tuberculosis carrying the rifampicin drug-resistance-conferring rpoB mutation H445Y is associated with suppressed immunity through type I interferons. mBio. 2023 Oct 31; 14(5):e0094623.
PMID: 37682004

A protocol to analyze single-cell RNA-seq data from Mycobacterium tuberculosis-infected mice lung.
A protocol to analyze single-cell RNA-seq data from Mycobacterium tuberculosis-infected mice lung. STAR Protoc. 2023 Sep 15; 4(3):102544.
PMID: 37659083

Rifampicin drug resistance and host immunity in tuberculosis: more than meets the eye.
Rifampicin drug resistance and host immunity in tuberculosis: more than meets the eye. Trends Immunol. 2023 09; 44(9):712-723.
PMID: 37543504

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